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Articles

Novel Cassette Assay To Quantify the Outer Membrane Permeability of Five β-Lactams Simultaneously in Carbapenem-Resistant Klebsiella pneumoniae and Enterobacter cloacae

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By Tae hwan Kim, Xun Tao, Bartolome Moya, Yuanyuan Jiao
| asm.org
Research Article | Therapeutics and Prevention Tae Hwan Kim, Xun Tao, Bartolome Moya, Yuanyuan Jiao, Kari B. Basso, Jieqiang Zhou, Yinzhi Lang, Dhruvitkumar S. Sutaria, Alexandre P. Zavascki, Afonso L. Barth, Stephanie M. Reeve, Herbert P. Schweizer, Deanna Deveson Lucas, John D. Boyce, Robert A. Bonomo, Richard E. Lee, Beom Soo Shin, Arnold Louie, George L. Drusano, Jürgen B. Bulitta Steven J.
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Comparable Efficacy and Better Safety of Double β-Lactam Combination Therapy versus β‑Lactam plus Aminoglycoside in Gram-Negative Bacteria in Randomized, Controlled Trials

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By Bartolome Moya, Mong-Jen Chen, Alexandre P Zavascki, Yuanyuan Jiao
| asm.org
Clinical Therapeutics Yuanyuan Jiao, Bartolome Moya, Mong-Jen Chen, Alexandre P. Zavascki, Hsinyin Tsai, Xun Tao, Dhruvitkumar S. Sutaria, Arnold Louie, John D. Boyce, Deanna Deveson Lucas, Tae Hwan Kim, Brian T. Tsuji, Robert A. Bonomo, George L. Drusano, Jürgen B. Bulitta DOI: 10.1128/AAC.00425-19 ABSTRACT There is a great need for efficacious therapies against Gram-negative bacteria.
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In Vitro and In Vivo Activities of β-Lactams in Combination with the Novel β-Lactam Enhancers Zidebactam and WCK 5153 against Multidrug-Resistant Metallo-β-Lactamase-Producing Klebsiella pneumoniae

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By Servicio de Microbiología, Unidad de Investigación, Bartolome Moya, Isabel M. Barcelo
| asm.org
Mechanisms of Action: Physiological Effects Bartolome Moya, Isabel M. Barcelo, Gabriel Cabot, Gabriel Torrens, Snehal Palwe, Prashant Joshi, Kushal Umarkar, Swapna Takalkar, Hariharan Periasamy, Sachin Bhagwat, Mahesh Patel, German Bou, Antonio Oliver DOI: 10.1128/AAC.00128-19 ABSTRACT Zidebactam and WCK 5153 are novel bicyclo-acyl hydrazide (BCH) agents that have previously been shown to act as β-lactam enhancer (BLE) antibiotics in Pseudomonas aeruginosa and Acinetobacter baumannii.
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