Bartłomiej Matejko

AFM atomic force microscopy AT after therapy ATP adenosine triphosphate BMI body mass index BT before therapy CTRL control group DD diabetes duration EPO erythropoietin GA glutaraldehyde RBCs red blood cells/erythrocytes SGLT2 sodium-glucose cotransporter-2 T1DM type 1 diabetes mellitus What is already known Diabetes influences negatively the elasticity of erythrocytes and the state of the cardiovascular system.

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1. Introduction Type 1 diabetes (T1D) accounts for approximately 10% of all types of diabetes. It mainly occurs in children and young people (of <30 years of age). Currently, type 1 diabetes is diagnosed in 10% of all diabetic patients and is the most common chronic disease of childhood in Poland. In the last 15 years alone, the number of cases in the group of preschool children has risen 4-fold and an increase of about 4% of pediatric patients (developmental age) has been noted each year.