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Bartosz Bartmanski on Muck Rack

Bartosz Bartmanski

As seen in: Science Magazine, BioRxiv
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Articles

Multi-omics profiling of cross-resistance between ceftazidime-avibactam and meropenem identifies common and strain-specific mechanisms in Pseudomonas aeruginosa clinical isolates

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By Bartosz Bartmanski, Steven Schmitt, Anja Boesch, Niranjan Ireddy
| BioRxiv
Abstract Pseudomonas aeruginosa is a highly versatile and resilient pathogen that can infect different tissues and rapidly develop resistance to multiple drugs. Ceftazidime-avibactam (CZA) is an antibiotic often used to treat multidrug resistant infections, however, the knowledge on the CZA resistance mechanisms in P. aeruginosa is limited. Here we performed laboratory evolution of eight clinical isolates of P.
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Systematic analysis of gut bacterial carcinogen metabolism and its functional consequences

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By Boyao Zhang, Michael T. Zimmermann, George-Eugene Maftei, Bartosz Bartmanski
| BioRxiv
Abstract Organic carcinogens, in particular DNA-reactive compounds, contribute to the irreversible initiation step of tumorigenesis through introduction of genomic instability. Although carcinogen bioactivation and detoxification by human enzymes has been extensively studied, carcinogen biotransformation by human-associated bacteria, the microbiota, has not yet been systematically investigated.
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