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Bartosz Bobula on Muck Rack

Bartosz Bobula

As seen in: MDPI, BioRxiv
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Articles

Activation of 5-HT7 receptors in the mouse dentate gyrus does not affect theta-burst-induced plasticity at the perforant path synapse

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By Marcin Siwiec, Michal Kielbinski, Bartosz Bobula, Nikola Multan
| BioRxiv
Abstract Background: The study examined the effects of 5-HT7 receptor activation on GABAergic transmission within the dentate gyrus and plasticity at the glutamatergic perforant path input. Methods: Immunofluorescence imaging was performed using transverse hippocampal slices from transgenic mice expressing green fluorescent protein (GFP) under the Htr7 promoter.
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Activation of 5-HT7 receptors in the mouse dentate gyrus selectively enhances GABAergic inhibition of hilar mossy cells without affecting plasticity at the perforant path synapse

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By Marcin Siwiec, Bartosz Bobula, Michal Kielbinski, Nikola Multan
| BioRxiv
Abstract Background: The study examined the effects of 5-HT7 receptor activation on GABAergic transmission within the dentate gyrus and plasticity at the glutamatergic perforant path input. Methods: Immunofluorescence imaging was performed using transverse hippocampal slices from transgenic mice expressing GFP under the Htr7 promoter.
Open in Who Shared Issue with article?

Maternal fluoxetine impairs synaptic transmission and plasticity in the medial prefrontal cortex and alters the structure and function of dorsal raphe nucleus neurons in offspring mice

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By Bartosz Bobula, Agnieszka Kania, Marcin Siwiec, Joanna Bak
| BioRxiv
Abstract Selective serotonin (5-HT) reuptake inhibitors (SSRIs) are a class of antidepressant drugs commonly prescribed to women during pregnancy and breastfeeding to treat depression. There is evidence that prenatal exposure to SSRIs may be associated with a higher risk of adverse cognitive outcomes and affective disorders in later life. In animal models, exposure to SSRIs during brain development results in behavioral alterations as well as structural abnormalities of cerebral cortical neurons.
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