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Bartosz Jary on Muck Rack

Bartosz Jary

As seen in: BioRxiv
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Articles

NF-kappaB and JNK pathways mediate metabolic adaptation upon ESCRT-I deficiency

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By Marta Wrobel, Michal Mazur, Jaroslaw Cendrowski, Bartosz Jary
| BioRxiv
Abstract Endosomal Sorting Complexes Required for Transport (ESCRTs) are crucial for delivering membrane receptors or intracellular organelles for lysosomal degradation. Yet, how ESCRT dysfunction affects cell metabolism remained elusive. To address this, we analyzed transcriptomes of cells lacking TSG101 or VPS28 proteins, components of ESCRT-I subcomplex.
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