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Temporal analysis of relative distances (TARDIS) is a robust, parameter-free alternative to single-particle tracking
New Results doi: https://doi.org/10.1101/2023.06.07.544011 Abstract In single-particle tracking (spt), individual particles are localized and tracked over time to probe their diffusion and molecular interactions. Temporal crossing of trajectories, blinking particles, and false-positive localizations present computational challenges that have remained difficult to overcome. Here, we introduce a robust, parameter-free alternative to spt: TARDIS.
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