Basil Britto Xavier

To fulfil the study’s objectives, we analysed biobank samples collected from three wards at the Italian 1560-bed Università Cattolica Sacro Cuore hospital “Policlinico A. Gemelli” (UCSC, Rome) in a 2-year (2010–2013), multicentre, prospective, longitudinal, observational cohort study (NCT01208519), and also utilised related datasets including epidemiological and clinical data. The clinical study protocol is described elsewhere [11].

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Abstract Background: The spread of antimicrobial resistance (AMR) poses a significant threat to global public health, primarily driven by the horizontal gene transfer of resistance genes via plasmids. Understanding the dynamics of plasmid transmission within (intra) and between (inter) bacterial species is crucial for developing effective countermeasures.