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Bedrettin Orhan

As seen in: Nature, Wiley Online Library
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Articles

Systemic inflammatory indices for predicting prognosis of myelofibrosis - Scientific Reports

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By Tuba Ersal, Vildan Özkocaman, İbrahim Ethem Pınar, Cumali Yalçın, Bedrettin Orhan, Ömer Candar, Sinem Çubukçu, Tuba Güllü Koca, Rıdvan Ali, Fazıl Çağrı Hunutlu, Şeyma Yavuz
| Nature Verified
Abstract The impact of inflammatory markers such as systemic immune-inflammation (SII) index and systemic inflammation response index (SIRI) on myelofibrosis (MF) prognosis was evaluated for the first time in this study. Data from 60 patients diagnosed with MF between March 2011 and September 2022 were retrospectively analyzed. In addition to disease-related markers, the impact of SII and SIRI on prognosis was evaluated. In our study, the overall median survival (OS) was 64 months.
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Potential modifications of the PLASMIC scoring system for predicting thrombotic thrombocytopenic purpura: Sometimes, less is more

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By Bedrettin Orhan, Vildan Özkocaman, Çiğdem Akdemir, Tuba Ersal
| Wiley Online Library Verified
Abstract Introduction Thrombotic thrombocytopenic purpura (TTP) is a life-threatening occlusive disease of the microcirculation characterized by systemic platelet plugs, organ ischemia, deep thrombocytopenia, and fragmentation of erythrocytes. One of the widely used scoring system to determine the clinical probability of TTP is the PLASMIC scoring system.
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