Beiying Deng
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Prevalence of fatty pancreas and its associations with pancreatic disease and metabolic disorders: a systematic review and meta-analysis of 124 studies
Abstract Background: The prevalence and impact of fatty pancreas (FP) on pancreatic and metabolic disorders remain incompletely characterized. We synthesized current evidence on FP prevalence and its associations with pancreatic and metabolic disorders. Methods: We performed a systematic review and meta-analysis of PubMed, Embase, and Cochrane Library through October 22, 2024.
Frontiers | Shared molecular features and potential diagnostic biomarkers between ulcerative colitis and sarcopenia: an integrative bioinformatics analysis with preliminary experimental validation
ORIGINAL RESEARCH article Front. Immunol., 15 April 2026 Sec.
UCP2 Upregulates ACSL3 to Enhance Lipid Droplet Release from Acinar Cells and Modulates the Sirt1/Smad3 Pathway to Promote Macrophage‐to‐Myofibroblast Transition in Chronic Pancreatitis
1 Introduction Chronic pancreatitis (CP) is a progressive, irreversible disease with a rising global incidence in recent years.[1] Its pathological features include acinar cell damage, immune cell infiltration, pancreatic atrophy, and interstitial fibrosis, which lead to both endocrine and exocrine pancreatic dysfunction.[2] Consequently, CP can result in pancreatic diabetes, pancreatic calcification, ductal stones, and an increased risk of pancreatic cancer.
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