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Belinda D Ortika on Muck Rack

Belinda D Ortika

As seen in: Nature, BioRxiv
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Articles

Epidemiological, immunological and virulence characteristics of persistent Streptococcus pneumoniae vaccine serotypes following vaccine introduction

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By Paige Skoko, Sam Manna, Laura K Boelsen, Jason Hinds, Stephanie Lo, Casey L Pell, Belinda D Ortika, Rachel Higgins, Eileen M. Dunne, Cattram Nguyen, Fiona Russell, Paul V. Licciardi, Claire von Mollendorf, Stephen Bentley, Catherine Satzke, Vicki Bennett-Wood, Hanwen Hou, Odgerel Tundev, E. Kim Mulholland, Tuya Mungun
| Nature Verified
Abstract Streptococcus pneumoniae vaccine serotypes can persist despite pneumococcal conjugate vaccine (PCV) introduction. To examine serotype persistence, we leverage 6,545 nasopharyngeal swabs collected from children hospitalised with pneumonia before and after PCV13 introduction in Mongolia. DNA microarray was used to identify changes in lineage composition within serotypes 6A, 6B, 14, 19F and 23F over the six-year surveillance period.
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Streptococcus pneumoniae serotype 33G: genetic, serological, and structural analysis of a new capsule type

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By Sam Manna, Joel P. Werren, Barbara Bellich, Belinda D Ortika
| BioRxiv
Abstract Streptococcus pneumoniae (the pneumococcus) is a human pathogen responsible for a spectrum of diseases such as pneumonia, sepsis, and meningitis. The capsule is the major pneumococcal virulence factor and is encoded by the capsular polysaccharide (cps) locus, a recombination hot spot that has resulted in over 100 distinct capsular polysaccharide types (serotypes) identified to date.
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