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Functionally linked amygdala and prefrontal cortical regions are innervated by both single and double projecting cholinergic neurons
Abstract Cholinergic cells have been proposed to innervate simultaneously those cortical areas that are mutually interconnected with each other. To test this hypothesis, we investigated the cholinergic innervation of functionally linked amygdala and prefrontal cortical regions. First, using tracing experiments, we determined that cholinergic cells located in distinct basal forebrain (BF) areas projected to the different nuclei of the basolateral amygdala (BLA).
Functionally linked amygdala and prefrontal cortical regions are innervated by both single and double projecting cholinergic neurons
Abstract Cholinergic cells have been proposed to project simultaneously to those cortical areas that are mutually interconnected with each other. We tested this hypothesis by investigating the cholinergic innervation of functionally linked cortical regions: the basal amygdala nucleus (BA) and dorsal part of the medial prefrontal cortex (dmPFC) as well as the basomedial amygdala nucleus (BMA) and ventral part of the mPFC (vmPFC).
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