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Benchaphorn Limcharoen on Muck Rack

Benchaphorn Limcharoen

As seen in: Nature, Wiley Online Library
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Articles

MGMT deficiency augments STING-mediated inflammatory responses accompanied by metabolic alterations in macrophages

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By Thitiporn Pattarakankul, Chanat Aonbangkhen, Benchaphorn Limcharoen, Takashi Kobayashi, Tanapat Palaga, Pornrat Kongkavitoon, Atsadang Boonmee, Benjawan Wongprom, Salisa Benjaskulluecha, Thadaphong Sukdee
| Nature Verified
Abstract The cGAS–STING pathway senses cytosolic DNA derived from both pathogens and host cells and plays a central role in innate immune responses. O6-methylguanine-DNA methyltransferase (MGMT) is a DNA repair enzyme that removes alkylation-induced DNA lesions and modulates macrophage inflammatory responses. Here, we investigated the role of MGMT in macrophage responses to STING activation.
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Genotype‐Dependent Modulation of Macrophage Apoptosis and T Lymphocyte Responses by Duck Tembusu Virus Potentially Contributes to Genotype‐Specific Immunopathogenesis

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By Teerawut Nedumpun, Re-Emerging Diseases, Re-emerging Infectious Diseases, Kanana Rungprasert, Benchaphorn Limcharoen
| Wiley Online Library Verified
1. Introduction Duck Tembusu virus (DTMUV) is an emerging avian pathogenic flavivirus that causes severe neurological disorders and acute egg drop syndrome in ducks and other avian species, including geese and chickens [1, 2]. Several studies have consistently shown that DTMUV primarily induces growth retardation and severe neurological signs in young ducks, and a marked reduction in egg production in laying ducks [3, 4].
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