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Bengul Gokbayrak on Muck Rack

Bengul Gokbayrak

As seen in: Nature, Wiley Online Library
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Articles

Shifted assembly and function of mSWI/SNF family subcomplexes underlie targetable dependencies in dedifferentiated endometrial carcinomas - Nature Genetics

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By Grace Xu, Bengul Gokbayrak, João Paulo, William W. Feng, Jun Qi, Jason L. Hornick, David L. Kolin, Steven Gygi, Yemin Wang
| Nature Verified
Abstract The mammalian (m)SWI/SNF family of chromatin remodelers govern cell type-specific chromatin accessibility and gene expression and assemble as three distinct complexes: canonical BRG1-associated or BRM-associated factor (cBAF), poly(bromo)-associated BAF (PBAF) and noncanonical BAF (ncBAF).
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Identification of selective SWI/SNF dependencies in enzalutamide-resistant prostate cancer - Communications Biology

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By Bengul Gokbayrak, Chia-Chi Huang, Paloma Cejas, Akane Kawamura, Tamer T. Onder, Tugba Bagci-Onder, James Lynch, Batuhan M. Kalkan
| Nature Verified
Abstract Enzalutamide is a potent second-generation antiandrogen commonly used to treat hormone-sensitive and castration-resistant prostate cancer (CRPC) patients. While initially effective, the disease almost always develops resistance. Given that many enzalutamide-resistant tumors lack specific somatic mutations, there is strong evidence that epigenetic factors can cause enzalutamide resistance.
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Prognostic values of molecular subtypes and SWI/SNF protein expression in de‐differentiated/undifferentiated endometrial carcinoma

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By Valerie Tao, Noorah Almadani, Bengul Gokbayrak, Eunice S Li
| Wiley Online Library Verified
ARID1A AT-rich interactive domain-containing protein 1A ARID1B AT-rich interactive domain-containing protein 1B CI confidence interval CIHR Canadian Institute of Health Research DD/UDEC de-differentiated and undifferentiated endometrial cancers EC endometrial carcinoma ER oestrogen receptor ESGO European Society of Gynaecological Oncology ESMO European Society of Medical Oncology ESTRO European Society of Radiation Oncology FFPE formalin-fixed paraffin-embedded FIGO International Federation...
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