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Beom Soo Jo

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Articles

A Multifunctional β‐Defensin‐3 Mimetic Peptide Modulates Host-Biofilm Interactions and Reduces Bone Loss in Periodontitis

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By Dong Woo Lee, Ji-Young Lee, Ji-young Lee Verified, Beom Soo Jo, Sanghui Seok
| Wiley Online Library Verified
1 Introduction Periodontitis is a chronic inflammatory disease characterized by progressive destruction of the periodontal supporting tissues, ultimately leading to tooth loss and contributing to systemic comorbidities such as cardiovascular disease, diabetes, and rheumatoid arthritis [1-4]. The disease is initiated by a dysbiotic microbial community within the periodontal pocket, where the accumulation of complex multispecies biofilms triggers persistent host immune activation [5, 6].
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