Bernardo Fontel Pompeu

Gabriel Ribeiro Belfort and Bernardo Fontel Pompeu contributed equally to this study. CONFLICT OF INTEREST STATEMENT F.B.F. serves as a speaker for Janssen Brazil, while the remaining authors declare no relevant conflicts of interest. All authors affirm their responsibility for the accuracy, integrity and impartiality of the data presented and the analyses discussed. DATA AVAILABILITY STATEMENT All data used in this review were extracted from published studies.

CI confidence interval DFS Disease-Free Survival FA Femoral Artery GSV great saphenous vein LSS Limb-Sparing Surgery OS overall survival PRISMA Preferred Reporting Items for Systematic Reviews and Meta-Analyses PROSPERO International Prospective Register of Systematic Reviews ROBINS-I V2 Risk of Bias In Non-randomized Studies of Interventions, Version 2 STS soft tissue sarcoma 1 Introduction Soft tissue sarcomas (STS) of the extremities are a heterogeneous group of malignant mesenchymal...

This study provides the first quantitative head-to-head comparison between topical and oral metronidazole after haemorrhoidectomy. By synthesizing all available randomized trials, it demonstrates equivalent short-term analgesic efficacy between routes, clarifies uncertainty in clinical practice, and refines post-operative pain management by addressing a previously unanswered question in the literature.