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Berrimah Veterinary Laboratories

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Articles

Comparative genomics of Japanese encephalitis virus shows low rates of recombination and a small subset of codon positions under episodic diversifying selection

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By Mark Sistrom, Hannah Andrews, Berrimah Veterinary Laboratories
| PLOS
Nucleotide diversity analysis showed relatively low rates of mutation across the genome (Fig 2, Graph B), with a notable decrease in π in NS2a and a notable increase in π in NS5. These rates of nucleotide diversity did not necessarily correspond with complementary changes in Dn-Ds ratios (Table 2). All genes deviated significantly from a model of neutral evolution, with strongly negative Dn-Ds values indicative of a strong overall signal of purifying selection. Table 2.
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