Bhavya K. Dawath on Muck Rack

Bhavya K. Dawath

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Multilayered regulation of GluK3 kainate receptors is mediated by Neto subunits and zinc - Communications Biology

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By Rajesh Vinnakota, Janesh Kumar, Bhavya K. Dawath, Anshul Assaiya, Suparna Bhar
| Nature
Abstract Kainate receptors (KARs), a distinct subfamily of ionotropic glutamate receptors, are critical modulators of synaptic transmission and network excitability. Their function is intricately regulated by auxiliary subunits and endogenous ions. The GluK3 subunit, in particular, exhibits unique gating and modulatory properties; however, the interplay between its known regulators, the Neto auxiliary proteins, and synaptic zinc remains poorly understood.
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