Biljana Novković on Muck Rack

Biljana Novković

As seen in: Nature
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Articles

Selphi, a tool for improving genotype imputation accuracy

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By Adriano De Marino, Abdallah Amr Mahmoud, Sandra Bohn, Jon Lerga-Jaso, Biljana Novković, Charlie Manson, Salvatore Loguercio, Andrew Terpolovsky, Ali Torkamani, Puya Yazdi, Mykyta Matushyn
| Nature Verified
Abstract Genotype imputation is a powerful tool for inferring missing genotype data in large-scale genetic studies. Over the last two decades, multiple imputation algorithms have been developed, steadily improving in speed and overall accuracy.
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Tracing human genetic histories and natural selection with precise local ancestry inference - Nature Communications

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By Jon Lerga-Jaso, Biljana Novković, Deepu Unnikrishnan, Varuna Bamunusinghe, Marcelinus R. Hatorangan, Haley Pedersen, Andrew Terpolovsky, Sandra Bohn, Abdallah A. Mahmoud, Karatuğ O. Bircan
| Nature Verified
Abstract Local ancestry inference is crucial for unraveling demographic histories, discovering selection signals, and including admixed individuals in genomic studies for improved equity and portability. To date, the precision and resolution of local ancestry inference were limited by technical and dataset issues.
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Retracing Human Genetic Histories and Natural Selection Using Precise Local Ancestry Inference

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By Jon Lerga-Jaso, Biljana Novković, Varuna Bamunusinghe, Deepu Unnikrishnan
| biorxiv.org
Abstract In an increasingly diverse world, including admixed individuals in genomic studies is imperative for equity and portability. A crucial first step is precise local ancestry inference (LAI). We have developed Orchestra, a LAI model with unprecedented accuracy, and trained on over 10,000 single-origin individuals from 35 worldwide populations.
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