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Articles

Therapeutic Potential of Selenium in Glioblastoma

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By Matthew W. Pitts, Reza Rastmanesh, BiMecon Ent
| Frontiers
Introduction Glioblastoma is by far the most common occurring malignant primary brain tumor in adults, affecting approximately 15% of all primary brain tumors diagnosed annually in the United States (Ostrom et al., 2019) and 20% in Europe (Wohrer et al., 2009; Darlix et al., 2016). Despite the aggressive multimodality strategy, the current prognosis of patients with glioblastoma (WHO Grade IV) is poor, with a median survival time of only 12–15 months (Wen and Kesari, 2008).
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