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Articles by Binbin Sun
Engineered MSC-exosomes as CRISPR-Cas9 delivery vectors for precision immunotherapy
Abstract Mesenchymal stem cell-derived exosomes (MSC-Exos) combined with CRISPR-Cas9 hold substantial therapeutic potential for immune-mediated diseases, although significant technical obstacles remain. This review presents a comprehensive analysis of strategies for engineering MSC-Exos as delivery vehicles for CRISPR-Cas9, with emphasis on cargo-loading methodologies and surface modifications that enable targeting specific immune cell populations.
Classification of Autism Spectrum Disorder in Children Using EEG Power Ratios Obtained During a Naturalistic Mentalizing Task
Key Words autism children EEG power Classification biomarker early screening Get full text access Log in, subscribe or purchase for full access. Reference 1. Hall-Lande, J. ∙ Esler, A.N. ∙ Hewitt, A. ... Age of initial identification of autism spectrum disorder in a diverse urban sample J Autism Dev Disord. 2021; 51:798-803 2. Dickinson, A. ∙ Daniel, M. ∙ Marin, A. ... Multivariate neural connectivity patterns in early infancy predict later autism symptoms Biol Psychiatry Cogn Neurosci Neuroimaging.
An Electroencephalographic Study of Sleep Spindle and Infraslow Oscillation in Children With Autism Spectrum Disorder
1 Introduction Autism spectrum disorder (ASD) is a fast-growing neurodevelopmental condition characterised by persistent deficits in social communication and the presence of restricted, repetitive behaviours (American-Psychiatric-Association 2013). According to recent estimates, approximately 1 in 31 children in the United States is diagnosed with ASD (Shaw et al. 2025), with incidence rates continuing to rise.
DE3S: Dual-Enhanced Soft-Sparse-Shape Learning for Medical Early Time-Series Classification
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MEET-Sepsis: Multi-Endogenous-View Enhanced Time-Series Representation Learning for Early Sepsis Prediction Representation Learning for Early Sepsis Prediction
arXiv:2510.15985 (cs) View PDF HTML (experimental) Comments: Subjects: Machine Learning (cs.LG); Artificial Intelligence (cs.AI) Cite as: arXiv:2510.15985 [cs.LG] (or arXiv:2510.15985v1 [cs.LG] for this version) https://doi.org/10.48550/arXiv.2510.15985 Submission history From: Zexi Tan [ view email] [v1] Mon, 13 Oct 2025 13:38:29 UTC (973 KB) Bibliographic Tools Bibliographic Explorer Toggle Bibliographic Explorer () Connected Papers Toggle Connected Papers (What is Connected Papers?)...
Understanding the Impact of Algorithmic Discrimination on Unethical Consumer Behavior
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Fabrication of Lightweight Polyimide Aerogels With Excellent Mechanical and Thermal Properties by Changing the Dianhydride Structures
Conflicts of Interest The authors declare no conflicts of interest. Supporting Information Filename Description app56823-sup-0001-Supinfo.docxWord 2007 document , 2.8 MB Figure S1. The optimized DFT structure of different dianhydrides. Figure S2. Calculated angles of repeating units in PI aerogels with different dianhydride structures. Figure S3. MPP and SDP values of different dianhydrides (atoms were colored according to the distance value). Figure S4.
A photocrosslinkable and anti-inflammatory hydrogel of loxoprofen-conjugated chitosan methacrylate
A photocrosslinkable and anti-inflammatory hydrogel of loxoprofen-conjugated chitosan methacrylate Polymer-drug conjugate is widely used for drug delivery. Herein, we report an injectable hydrogel for local delivery of nonsteroidal anti-inflammatory drugs (NSAIDs) using chitosan (CS) as a carrier polymer. Loxoprofen (LOX) was conjugated to the backbones of CS via carbodiimide chemistry to obtain LOX-CS conjugate.
Minerals | Free Full-Text | Enrichment Characteristics and Ecological Risk Assessment of Heavy Metals in a Farmland System with High Geochemical Background in the Black Shale Region of Zhejiang, China
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Lightweight Porous Carbon Foams via Pyrolysis of Robust Polyimide Foams for Efficient Broadband Microwave Absorption
Download Hi-Res ImageDownload to MS-PowerPointCite This:Ind. Eng. Chem. Res. 2024, XXXX, XXX Terms & Conditions Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may be downloaded by article for research use (if there is a public use license linked to the relevant article, that license may permit other uses).
Identification of genes associated with the silk gland size using multi‐omics in silkworm (Bombyx mori)
CONFLICT OF INTEREST STATEMENT The authors have no conflicts of interest to declare. Supporting Information Filename Description imb12870-sup-0001-AppendixS1.docxWord 2007 document , 1.4 MB Appendix S1. Supporting Information. imb12870-sup-0002-TableS4.xlsxExcel 2007 spreadsheet , 3.7 MB Table S4. Summary of expression of A798, A306 and XH. imb12870-sup-0003-TableS5.xlsxExcel 2007 spreadsheet , 1,015.6 KB Table S5. Differentially expressed genes and proteins in HD and MD. REFERENCES , , , , , et al.
A Multifunctional Asymmetric Fabric for Sustained Electricity Generation from Multiple Sources and Simultaneous Solar Steam Generation
Abstract Harvesting electrical energy from water and moisture has emerged as a novel ecofriendly energy conversion technology. Herein, a multifunctional asymmetric polyaniline/carbon nanotubes/poly(vinyl alcohol) (APCP) that can produce electric energy from both saline water and moisture and generate fresh water simultaneously is developed.
Design of Dynamic Multi-Obstacle Tracking Algorithm for Intelligent Vehicle
1. Introduction Intelligent vehicles play an important role in reducing traffic accidents, solving traffic congestion and reducing pollution in the environment, and they are an important direction for the development of the automotive industry. Intelligent vehicles are composed of four parts, including environmental perception, localization, path planning and control [1].
Electrospinning Inorganic Nanomaterials to Fabricate Bionanocomposites for Soft and Hard Tissue Repair
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Design and Performance Analysis of Super Highspeed Flywheel Rotor for Electric Vehicle
The optimal design of a super highspeed flywheel rotor could improve flywheel battery energy density. The improvement of flywheel battery energy density could enhance the performance of the flywheel lithium battery composite energy storage system. However, there are still many problems in the structure, material and flywheel winding of super highspeed flywheels.
Research on 3D Point Cloud Data Preprocessing and Clustering Algorithm of Obstacles for Intelligent Vehicle
Environment perception is the foundation of the intelligent driving system and is a prerequisite for achieving path planning and vehicle control. Among them, obstacle detection is the key to environment perception.
Impacts of Proteins on Dissolution and Sulfidation of Silver Nanowires in an Aquatic Environment: Importance of Surface Charges
With increasing utilization of silver nanomaterials, growing concerns are raised on their deleterious effects to the environment.
Lateral Size Dependent Colloidal Stability of Graphene Oxide in Water: Impacts of Protein Properties and Water Chemistry
Lateral Size Dependent Colloidal Stability of Graphene Oxide in Water: Impacts of Protein Properties and Water Chemistry Binbin Sun, Yinqing Zhang, Qing Liu, Chaorui Yan, Bowen Xiao, Jing Yang, Menglin Liu and Lingyan Zhu Abstract The effects of model proteins (OVA: ovalbumin, and BSA: bovine serum albumin) on the colloidal stability of graphene oxide (GO) with different lateral sizes (around 1000, 500, 350 and 200 nm, respectively) were investigated.
Impacts of surfactants on dissolution and sulfidation of silver nanowires in aquatic environments
Due to the excellent properties, silver nanowires (AgNWs) are applied increasingly in many optical and electronic products, and may be inevitably discharged in aquatic environments. Dissolution and sulfidation are two of the most important processes of AgNWs occurring in aquatic environments and may significantly affect their fate and toxicities.
Concentration Dependent Effects of Bovine Serum Albumin on Graphene Oxide Colloidal Stability in Aquatic Environment
The impacts of a model globular protein (bovine serum albumin, BSA) on aggregation kinetics of graphene oxide (GO) in aquatic environment were investigated through time-resolved dynamic light scattering at pH 5.5. Aggregation kinetics of GO without BSA as a function of electrolyte concentrations (NaCl, MgCl , and CaCl ) followed the traditional Derjaguin–Landau–Verwey–Overbeek (DLVO) theory, and the critical coagulation concentration (CCC) was 190, 5.41, and 1.61 mM, respectively.
Laminin-coated Nerve Guidance Conduits Based on Poly(L-lactide-co-glycolide) Fibers and Yarns for Promoting Schwann Cells Proliferation and Migration
To develop an effective nerve guidance conduit with cooperated effect of topological structure and biological cues for promoting Schwann cells (SCs) proliferation and migration, a laminin-coated and yarn-encapsulated poly(L-lactide-co-glycolide) (PLGA) nerve guidance conduit (LC-YE-PLGA NGC) was fabricated in this study. The PLGA fiber yarns were fabricated by a double-nozzle electrospinning system and then the PLGA fibrous outer layer was collected by the general electrospinning method.
Application of a bilayer tubular scaffold based on electrospun poly(l-lactide-co-caprolactone)/collagen fibers and yarns for tracheal tissue engineering - Journal of Materials Chemistry B (RSC Publishing)
A bilayer tubular scaffold (BLTS) was prepared by electrospinning, which consisted of poly(l-lactide-co-caprolactone) (P(LLA-CL)) and collagen submicron fibers and micron yarns. Then, autologous tracheal epithelial cells and chondrocytes were separately seeded on the two layers of BLTS. After culturing for 7 days, the cell-seeded BLTS (CS-BLTS) was implanted and wrapped in rat trachea fascia for pre-vascularization.
Polypyrrole-Coated Poly(l-lactic acid-co-ε-caprolactone)/Silk Fibroin Nanofibrous Membranes Promoting Neural Cells Proliferation and Differentiation with Electrical Stimulation - Journal of Materials Chemistry B (RSC Publishing)
Polypyrrole (Ppy), as a conductive polymer, was commonly used for nerve tissue engineering because of good conductivity and non-cytotoxicity. To avoid the inconvenience of Ppy processing, it was coated on electrospun poly (l-lactic acid-co-ε-caprolactone)/silk fibroin (PLCL/SF) nanofibers via in situ oxidative polymerization of pyrrole monomers in this study.
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