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Shuying Feng

As seen in: Wiley Online Library, Frontiers, MDPI
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Articles

Engineered MSC-exosomes as CRISPR-Cas9 delivery vectors for precision immunotherapy

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By Dandan Guo, Wei Zhang, Wenbo Dou, Yitong Yang, Binbin Sun, Mengyu Qiu, Kai Wang, Jianjun Zhai, Shuying Feng
| Frontiers
Abstract Mesenchymal stem cell-derived exosomes (MSC-Exos) combined with CRISPR-Cas9 hold substantial therapeutic potential for immune-mediated diseases, although significant technical obstacles remain. This review presents a comprehensive analysis of strategies for engineering MSC-Exos as delivery vehicles for CRISPR-Cas9, with emphasis on cargo-loading methodologies and surface modifications that enable targeting specific immune cell populations.
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A new perspective on Wendan decoction: attenuation of CUMS-induced anxiety in mice by regulating gut microbiota and neuroinflammation

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By Zixuan Guo, Qianqian Wang, Baiyan Wang, Boyi Zhang, Jiawei Huang, Yuanyuan Niu, Junhong Huang, Zilong Wang, Shuying Feng, Yunge Cao
| Frontiers
1 Introduction Anxiety is an evolutionarily conserved adaptive response that serves to shield organisms from potentially life-threatening situations. However, when anxiety becomes chronic and dysregulated, it is classified as a pathological condition, profoundly impairing daily subjective experiences, behavior, and overall mental health. Anxiety is the most prevalent mental health disorder globally, affecting an estimated 25% of the population worldwide (Chellappa and Aeschbach, 2022).
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Molecular Dynamics Study on the Decomposition of IHEM-1 under Impact Loading: Comparison with Traditional Energetic Materials

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By Shuang Wu, Xifeng Liang, Jiaqiang Wang, Shuying Feng
| dx.doi.org
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