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Biniam Mathewos Tebeje on Muck Rack

Biniam Mathewos Tebeje

As seen in: BioRxiv
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Articles

Growing Macrophages Regulate High Rates of Solute Flux by Pinocytosis

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By Joel A. Swanson, Biniam Mathewos Tebeje, Natalie W Thiex
| BioRxiv
Abstract In metazoan cells, growth factors stimulate solute ingestion by pinocytosis. To examine the role of pinocytosis in cell growth, this study measured cell proliferation and the attendant rates of solute flux by pinocytosis in murine macrophages in response to the growth factor colony-stimulating factor-1 (CSF1). During CSF1-dependent growth in rich medium, macrophages internalized 72 percent of their cell volume in extracellular fluid every hour.
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