Birgit Roth Z'graggen on Muck Rack

Birgit Roth Z'graggen

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Effects of sevoflurane and its metabolite hexafluoroisopropanol on hypoxia/reoxygenation-induced injury and mitochondrial bioenergetics in murine cardiomyocytes

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By Birgit Roth Z'graggen, Beatrice Beck-Schimmer, Martin Schläpfer
| bjaopen.org
Analysis of mitochondrial bioenergetics The XFp Extracellular Flux Analyzer (Seahorse; Bucher Biotec AG, Basel, Switzerland) allows real-time cellular oxygen consumption rate (OCR) monitoring and extracellular pH (extracellular acidification rate [ECAR]), which provides information about the mitochondrial energy state. The variables are determined using continuous oxygen concentration measurement and proton flux in the cell supernatant over time.
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