Birgitta Gleeson

FF is a trustee of Neotree, a UK registered charity that provides technology, software information, education and support to newborn healthcare workers and medical practitioners in low resource settings (charity number: 1186748). All other authors declare no conflict of interest. The funders had no role in the design of the study, the collection, analyses, or interpretation of data, the writing of the manuscript, or the decision to publish the results.

diagnostics and tools other diagnostic or tool infections, diseases, disorders, injuries SUMMARY BOX Low- and middle-income countries (LMICs) bear the greatest burden of neonatal mortality, with sepsis being a major contributor. Non-specificity of signs, and the absence of a definitive diagnostic, present a challenge to the identification of sepsis and can lead to underdiagnosis or overdiagnosis, both of which can have harmful consequences.