BiXin Shen

Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data generated and/or analyzed during the current study are available from the corresponding author upon request. Supporting Information Filename Description bmc70476-sup-0001-Supplementary_Figure.tifTIFF image, 590.7 KB Figure S1: The expression of p-AKT1 (Ser473) was detected in UC-SDS rats treated with SLBZP. All data are expressed as mean ± SD.

Currently, phototherapy initiated by local irradiation of near-infrared laser has emerged as a promising strategy for cancer treatment because of low toxicity. However, how to specifically deliver a sufficient dose of photosensitizers to tumor focus is one key question for effective phototherapy. Herein, indocyanine green (ICG), a FDA-approved photosensitizer, was firstly encapsulated in inner aqueous compartment of liposome (ICG-LIP) to improve its stability.