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Blenda de Jesus

As seen in: Oxford Academic
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Articles

Early transcriptional signature in chikungunya predicts chronic arthralgia and reveals deficient antiviral response

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By de Moraes, da Silva, Blenda de Jesus
| Oxford Academic Verified
Post-acute viral syndromes are increasingly recognised as causes of prolonged disability, with a notably higher prevalence in women. This study investigated the immune signature of individuals who progressed to chronic chikungunya (CC), a condition characterised by persistent arthralgia and examined the role of biological sex in disease outcomes. We analysed peripheral blood mononuclear cells from patients, recruited between 2016 and 2020, sampled within seven days of disease onset.
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