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Bogdan R. Brutiu on Muck Rack

Bogdan R. Brutiu

As seen in: Nature, Wiley Online Library, ACS Publications
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Articles

Developing a new cleavable crosslinker reagent for in-cell crosslinking - Communications Chemistry

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By Fränze Müller, Bogdan R. Brutiu, Micha J. Birklbauer, Manuel Matzinger, Viktoria Dorfer, Nuno Maulide
| Nature Verified
Abstract Crosslinking mass spectrometry (XL-MS) is a powerful technology that recently emerged as an essential complementary tool for elucidating protein structures and mapping interactions within a protein network. Crosslinkers which are amenable to post-linking backbone cleavage simplify peptide identification, aid in 3D structure determination and enable system-wide studies of protein-protein interactions (PPIs) in cellular environments.
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Regioselective Synthesis of β,γ-Unsaturated Amides from Unactivated Alkenes

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By Sabela Vega-Ces, Bogdan R. Brutiu, Daniel Kaiser, Nuno Maulide
| dx.doi.org
Carboxamides have gained attention as important motifs in drug design (1−3) (where they contribute to the stability, bioavailability, and conformational control of therapeutic compounds), in materials science (as high-stability polymers (4−6) or biomedical materials (7−9)), and as useful ligands in catalysis.
Open in Who Shared Issue with article?

Regioselective Synthesis of β,γ-Unsaturated Amides from Unactivated Alkenes

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By Bogdan R. Brutiu, Daniel Kaiser, Nuno Maulide, Sabela Vega-Ces
| ACS Publications
Carboxamides have gained attention as important motifs in drug design (1−3) (where they contribute to the stability, bioavailability, and conformational control of therapeutic compounds), in materials science (as high-stability polymers (4−6) or biomedical materials (7−9)), and as useful ligands in catalysis.
Open in Who Shared Issue with article?
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