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Boina Baoyinna on Muck Rack

Boina Baoyinna

As seen in: MDPI
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Biomedicines | Free Full-Text | Non-Lethal Doses of RSL3 Impair Microvascular Endothelial Barrier through Degradation of Sphingosie-1-Phosphate Receptor 1 and Cytoskeletal Arrangement in A Ferroptosis-Independent Manner

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By Patrick Oliver, Boina Baoyinna, Jiaxing Miao, Qinmao Ye
| MDPI
1. Introduction Endothelial cells form a continuing monolayer that constitutes the inner cellular lining of vascular vessels. Macromolecules and blood cells in the flowing blood are prevented from leaking into surrounding tissue by the confluent endothelial barrier, which acts as the gatekeeper of vascular homeostasis [1,2,3]. In the setting of acute inflammatory disease, microvascular endothelial permeability is abnormally increased, causing nearby tissue edema.
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