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Bomsoo Cho

As seen in: Nature, Texas Medical Center
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Articles

Cell autonomous polarization by the planar cell polarity signaling pathway - Nature Communications

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By Silas Boye Nissen, Bomsoo Cho
| Nature Verified
Abstract As epithelial cells polarize in the tissue plane, the Planar Cell Polarity (PCP) signaling module segregates two distinct molecular subcomplexes to opposite sides of cells. Homodimers of the atypical cadherin Flamingo form bridges linking opposite complexes in neighboring cells, coordinating their direction of polarization. Feedback is required for cell polarization, but whether feedback requires intercellular and/or intracellular pathways is unknown.
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"An ACE2 Decamer Viral Trap as a Durable Intervention Solution for Curr" by Hailong Guo, Bomsoo Cho et al.

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By Hailong Guo, Bomsoo Cho, Paul R. Hinton, Sijia He
| Texas Medical Center
Abstract The capacity of SARS-CoV-2 to evolve poses challenges to conventional prevention and treatment options such as vaccination and monoclonal antibodies, as they rely on viral receptor binding domain (RBD) sequences from previous strains. Additionally, animal CoVs, especially those of the SARS family, are now appreciated as a constant pandemic threat.
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Protein phosphatase 1 regulates core PCP signaling

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By Bomsoo Cho, Alexis T. Weiner, Silas Boye Nissen, Irene Ojeda Naharros
| embopress.org
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