Boris-Stephan Rauchmann on Muck Rack

Boris-Stephan Rauchmann

As seen in: Nature, Wiley Online Library, Neurology
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Articles

Smartphone-based detection of subtle memory decline in prodromal Alzheimer’s disease

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By Sarah Polk, Lindsay Clark Verified, Luca Kleineidam, Wenzel Glanz, Michaela Butryn, Robert Perneczky, Katharina Buerger, Klaus Fliessbach, Christoph Laske, Annika Spottke, Anja Schneider, Jens Wiltfang, Stefan J. Teipel, Claudia Bartels, Ayda Rostamzadeh, Daniel Janowitz, Boris-Stephan Rauchmann, Frederic Brosseron, Michael Wagner, Ingo Frommann, Melina Stark, Matthias Schmid Verified, Björn H. Schott, Sterling Johnson, Frank Jessen, Emrah Düzel, David Berron, Kristin Basche, Ingo Kilimann, Sebastian Sodenkamp, Marie Coenjaerts
| Nature Verified
Abstract The slow progression of Alzheimer’s disease (AD) poses a challenge for the quantification of early disease-driven cognitive decline. Here, we show that frequently administered remote and unsupervised digital cognitive assessments can detect differences in cognitive decline within 30 weeks in early AD.
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Early Locus Coeruleus noradrenergic axon loss drives olfactory dysfunction in Alzheimer’s disease - Nature Communications

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By Theresa Niedermeier, Felix L. Strübing, Boris-Stephan Rauchmann, Yannik Tillmann, Nicolas F. Landgraf, Karin Wind-Mark, Gloria Biechele, Selim Guersel, Carolin Kurz, Yuan Shi, Richard Banati, Guo-Jun Liu, Robert Perneczky, Jonas J. Neher, Sabina Tahirovic, Matthias Brendel, Jochen Herms
| Nature Verified
Abstract Alzheimer’s disease (AD) often begins with non-cognitive symptoms such as olfactory deficits, which can predict later cognitive decline, though the mechanisms remain unclear. Pathologically, the brainstem locus coeruleus (LC), the main source of the neurotransmitter noradrenalin (NA) modulating olfactory information processing is affected early.
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Frequency and Longitudinal Course of Motor Signs in Genetic Frontotemporal Dementia

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By Boris-Stephan Rauchmann, Nicolai Franzmeier, Sonja Schönecker, Francisco J. Martinez-Murcia
| Neurology Verified
Statistical Analysis Data were analyzed using IBM SPSS Statistics for Windows (version 25.0; IBM Corp., Armonk, NY). Nondichotomized mean scores of demographic data were compared via the Kruskal-Wallis test and post hoc Bonferroni-corrected Mann-Whitney test. Chi-square analysis was used to check for significant differences in sex. Standard statistical significance level was set at p < 0.05.
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