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Boy. B. Rozenberg on Muck Rack

Boy. B. Rozenberg

As seen in: Color Research & Application
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Improving the barrier function of damaged cultured urothelium using chondroitin sulfate

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By J. A. Schalken, Boy. B. Rozenberg
| Color Research & Application Verified
Aims To determine whether glycosaminoglycan (GAG) replenishment is able to improve recovery of a deficient urothelial barrier, chondroitin sulfate (CS) instillations were tested using an in vitro model. Porcine urothelial cells (Ucells) were terminally differentiated in culture conditions to construct a urothelial layer with a functional barrier. This layer was damaged to compromise barrier function to simulate a key characteristic of bladder pain syndrome/interstitial cystitis.
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