Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile
Articles by Brain imaging
Childhood Maltreatment and Deviations from Normative Brain Structure: A Mega-Analysis of 3,711 Individuals from the ENIGMA MDD and ENIGMA PTSD Working Groups
Keywords Childhood maltreatment brain morphometry normative modeling sex differences major depressive disorder PTSD Introduction Early life adversity (ELA), particularly childhood maltreatment (CM) such as abuse and neglect, is common, affecting more than two-thirds of the general population (1, 2).
Progress and ongoing conceptual challenges “on the way to integrative human neuroscience”–ten years after
Abstract Ten years ago, we published a position paper in this journal, criticizing reductionist claims of neurobiology related to mental disorders and important theoretical concepts like free will. Our interdisciplinary group of experts highlighted the need for and the challenges of integrating different approaches and system levels in neuroscience.
Brain Imaging and Neuroimaging Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, Segmented By Imaging Type, By End User, By Region & Competition, 2021-2031F
The Global Brain Imaging and Neuroimaging Market is projected to expand from USD 12.64 Billion in 2025 to USD 18.40 Billion by 2031, reflecting a compound annual growth rate of 6.46%. These products encompass a variety of non-invasive diagnostic technologies, such as computed tomography and magnetic resonance imaging, which are designed to visualize the structural and functional status of the central nervous system.
Domain-Specific Efficacy of Accelerated Repetitive Transcranial Magnetic Stimulation in Neuropsychiatric Disorders: A Systematic Review and Meta-Analysis
Keywords accelerated repetitive transcranial magnetic stimulation neuromodulation neuroplasticity transdiagnostic symptom domains neuropsychiatric disorders translational neuroscience Get full text access Log in, subscribe or purchase for full access. References 1. Bolognini, N. ∙ Ro, T. Transcranial magnetic stimulation: disrupting neural activity to alter and assess brain function J Neurosci. 2010; 30:9647-9650 2. Fitzsimmons, SMDD ∙ Oostra, E. ∙ Postma, T.S. ...
Data‐Driven Approach to Dynamic Resting State Functional Connectivity in Post‐Traumatic Stress Disorder: An ENIGMA‐PGC PTSD Study
1 Introduction Globally, 70% of individuals are estimated to be exposed to trauma, and 40% are estimated to experience direct interpersonal violence (Kessler et al. 2017). While the majority of individuals are resilient after trauma exposure, a substantial minority develop chronic posttraumatic stress disorder (PTSD) and related disorders (Bonanno 2021; Southwick et al. 2014; Valiente et al. 2021).
Catatonia: What Else Matters?
Relevant conflicts of interest/financial disclosures: D.H. has received honoraria from Rovi and Teva, speaker fees from DGPPN, and editorial fees from Elsevier and Thieme Verlag. A.M.-L. has received consultant fees from Agence Nationale de la Recherche, the Brain Mind Institute, Brainsway, CISSN (Catania International Summer School of Neuroscience), Daimler und Benz Stiftung, Fondation FondaMental, Hector Stiftung II, Janssen-Cilag GmbH, Lundbeck A/S, Lundbeckfonden, Lundbeck Int.
Mobile Gamma Cameras Market Global outlook 2024 to 2031
Global Mobile Gamma Cameras Market Size 2024 that provides crucial details on company opportunities, growth plans, trends, innovations, competitive landscape in 2024, and the geographic outlook. Based on relevant market and regional segmentation, a thorough assessment of this worldwide market includes the historical analysis of this market (from 2024 to 2031) and develops reliable and approximate timeline estimations up to 2031.
Prediction of amyloid and tau brain deposition and cognitive decline in people with Down syndrome using plasma biomarkers: a longitudinal cohort study
Introduction Down syndrome is considered a genetic form of Alzheimer's disease, with more than 90% of adults with Down syndrome developing Alzheimer's disease-related pathological changes by the age of 40 years, likely due to an additional copy of the amyloid precursor protein-encoding gene located on chromosome 21.1–3 Despite some differences in the timing, spatial distribution, or magnitude, the overall progression of amyloid-β (Aβ) and tau brain deposition (measured with PET) is relatively...
The implications of amyloid-β pathology: only time will tell
This scientific commentary refers to ‘Characterizing brain tau and cognitive decline along the amyloid timeline in Alzheimer’s disease’ by Cody et al. (https://doi.org/10.1093/brain/awae116). The current conceptualization of Alzheimer’s disease is strongly driven by the amyloid cascade hypothesis,1 which has provided the leading framework for investigating and understanding Alzheimer’s disease pathophysiology.
Parkinsonism, Psychomotor Slowing, Negative and Depressive Symptoms in Schizophrenia Spectrum and Mood Disorders: Exploring Their Intricate Nexus Using a Network Analytic Approach
Parkinsonism, psychomotor slowing, negative and depressive symptoms show evident phenomenological similarities across different mental disorders. However, the extent to which they interact with each other is currently unclear. Here, we hypothesized that parkinsonism is an independent motor abnormality showing limited associations with psychomotor slowing, negative and depressive symptoms in schizophrenia spectrum (SSD), and mood disorders (MOD).
tDCS reduces depression and state anxiety symptoms in older adults from the augmenting cognitive training in older adults study (ACT)
Highlights • Active tDCS yielded greater reductions in depression and state anxiety than sham. • These reductions were largest for those with mild depression and moderate/severe state anxiety. • tDCS effects on state anxiety remained at one-year for those with moderate/severe state anxiety. • There were no significant tDCS effects on trait anxiety. • tDCS effectively reduces psychological symptoms in a community sample of older adults.
Plasma Biomarker Strategy for Selecting Patients With Alzheimer Disease for Antiamyloid Immunotherapies
Key Points Question Can plasma biomarkers serve as prescreening tools to identify individuals suitable for treatment with antiamyloid immunotherapies in Alzheimer disease, ie, amyloid β (Aβ)–positive individuals who do not yet have too much tau in the brain? Findings This cohort study demonstrated the efficacy of using plasma p-tau217 values to both rule out Aβ-negative individuals and identify Aβ-positive individuals who are likely to have high tau burden.
Editorial: Affective processing and non-invasive brain stimulation, volume II
Affective processing plays a crucial role in human life. Deficits in affective processing are accompanied by mental problems including depression, anxiety, and addiction. Non-invasive brain stimulation methodologies such as transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) have become more and more popular in modulating a wide range of cognitive processing.
Dopamine Transporter Availability in Early Parkinson's Disease is Dependent on Sunlight Exposure
Dopamine transporter (DAT) single photon emission computed tomography (SPECT) imaging is a valuable tool used in routine practice to evaluate whether parkinsonian signs are accompanied by degeneration of nigrostriatal dopaminergic neurons.1 Interestingly, striatal DAT availability in healthy controls (HCs) also show a high inter-individual variability.2 In Parkinson's disease (PD) patients, variability in striatal DAT reductions cannot be explained solely by the severity of motor symptoms.3...
GABAA receptor availability relates to emotion-induced BOLD responses in the medial prefrontal cortex: simultaneous fMRI/PET with [11C]flumazenil
1. Introduction The basis of any brain function results from neural signaling and the associated interplay of neurotransmitters that are organized in large-scale networks. These networks cause fluctuations in the cerebral metabolic rate of oxygen consumption, inducing changes in the blood content of deoxyhaemoglobin, as well as changes in blood flow and volume, representing the basis of the fMRI BOLD signal (Lauritzen et al., 2012).
Cocaine use is associated with cerebral white matter hyperintensities in HIV disease
Materials and Methods The data in this report were collected as part of a larger project on neuroimaging and immunological features of NCI in PWH.58 The study was approved by the Duke Health Institutional Review Board, and all participants provided written, informed consent. Participants PWH aged 18–59 years were recruited from infectious diseases clinics in the Raleigh/Durham area of North Carolina, USA.
fMRI changes during multi-limb movements in Parkinson’s disease
1. Introduction Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by the gradual loss of dopamine-producing neurons (Fearnley and Lees, 1991; Obeso et al., 2008; Kordower et al., 2013).
Sharing brain imaging data in the Open Science era: how and why?
Summary The sharing of human neuroimaging data has great potential to accelerate the development of imaging biomarkers in neurological and psychiatric disorders; however, major obstacles remain in terms of how and why to share data in the Open Science context. In this Health Policy by the European Cluster for Imaging Biomarkers, we outline the current main opportunities and challenges based on the results of an online survey disseminated among senior scientists in the field.
Attributional negativity bias and acute stress disorder symptoms mediate the association between trauma history and future posttraumatic stress disorder
Filename Description jts22942-sup-0001-SuppMat.docx142.4 KB Online Appendix Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Tau protein spreads through functionally connected neurons in Alzheimer’s disease: a combined MEG/PET study
When you visit web sites, they may store or retrieve data in your web browser. This storage is often necessary for basic functionality of the web site or the storage may be used for the purposes of marketing, analytics, and personalization of the web site such as storing your preferences.
Tau protein spreads through functionally connected neurons in Alzheimer’s disease: a combined MEG/PET study
When you visit web sites, they may store or retrieve data in your web browser. This storage is often necessary for basic functionality of the web site or the storage may be used for the purposes of marketing, analytics, and personalization of the web site such as storing your preferences.
Genetically identical twin-pair difference models support the amyloid cascade hypothesis
PDF Split View Article contents Figures & tables Video Audio Supplementary Data Emma M Coomans , Genetically identical twin-pair difference models support the amyloid cascade hypothesis, Brain, Volume 146, Issue 9, September 2023, Pages 3735–3746, https://doi.org/10.1093/brain/awad077 Close Alzheimer’s disease, amyloid-β, tau, neurodegeneration, cognition, identical twins Introduction The amyloid cascade hypothesis has provided the leading framework for investigating and understanding...
The amyloid imaging for the prevention of Alzheimer's disease consortium: A European collaboration with global impact
1. The scientific landscape of Alzheimer's disease Dementia is a major cause of disability, dependency, and mortality in the elderly population. It is estimated that by the year 2050, up to 150 million individuals will be affected by this condition (1). Care of these patients comes with considerable societal and economic impact, stressing the importance of optimal diagnostics and the availability of disease-modifying therapies.
Plastic Netting Market Size, Share, Growth Statistics By Top Key Players | EXPO-NET, NorPlex Inc., Tenax
The global Plastic Netting market size was valued at USD 3177.9 million in 2021 and is expected to expand at a CAGR of 3.91percent during the forecast period, reaching USD 3999.5 million by 2027. Final Report will add the analysis of the impact of Russia-Ukraine War and COVID-19 on this Plastic Netting Industry.
Imaging blood-brain barrier dysfunction: a state-of-the-art review from a clinical perspective
Paulien Moyaert1, 2, 3*, Beatriz Padrela4, 5, Catherine Morgan6, Jan Petr7, Jan Versijpt3, Frederik Barkhof4, 5, 8, Michael T. Jurkiewicz9, Xingfeng Shao10, Olujide Oyeniran2, 11, Tabitha Manson6, 12, Danny J. Wang10, Matthias Günther13, Eric Achten1, Henk J. Mutsaerts4, 5 and Udunna C.
Mild Dehydration: Is It Causing Memory Loss, Depression, Anxiousness, or Focus Problems?
If you notice that your mood is low or your anxiety level is high, or you’re struggling to focus mentally or having trouble with recall, or are just generally feeling irritable, it could be that you need to drink some water. Even mild dehydration can dampen your mood and more, causing you to feel more depressed, anxious, tense, irritable, or antagonistic. That’s in addition to zapping your energy, increasing pain levels, and compromising your ability to concentrate, according to recent research.
Corrigendum: Absolute winding number differentiates mouse spatial navigation strategies with genetic risk for Alzheimer's disease
In the published article there was an error in the figures. Figure 2 was omitted, and Figure 3 was mistakenly used instead of Figure 2. The corrected Figure 2 appears below. Figure 2. Learning trials. Mice swam shorter distances over the 5 testing days until reaching the hidden platform, indicating that they were learning (A,B). Meanwhile, the percentage time swam in the target quadrant increased with time (C,D).
Advanced intraoperative MRI in pediatric brain tumor surgery.
Pien E. Jellema1, 2*, Jannie P. Wijnen2, Alberto De Luca2, 3, Henk J. Mutsaerts4, 5, Iris V. Obdeijn2, Kirsten M. van Baarsen1, 6, Maarten H. Lequin1, 7 and Eelco W.
Absolute Winding Number Differentiates Mouse Spatial Navigation Strategies With Genetic Risk for Alzheimer’s Disease
Impact Factor 4.677 | CiteScore 5.4 More on impact › TABLE OF CONTENTS Alexandra Badea1,2,3,4*†, Didong Li5,6†, Andrei R. Niculescu1, Robert J. Anderson1, Jacques A. Stout3, Christina L. Williams7, Carol A. Colton2, Nobuyo Maeda8 and David B.
The Four Circles of Brain Health and Illness
Many people think mental health problems stem only from the mind. A growing number of people agree that there is a mind-body connection in terms of overall wellness. This is true, but there’s even more to mental well-being. There are actually four aspects of a whole life that influence mental health, cognitive health, and behavioral health in either a positive way or a negative way. At Amen Clinics, this is referred to as the Four Circles of Mental Health.
Activity in the Fronto-Parietal and Visual Cortex Is Modulated by Feature-Based Attentional Weighting
Introduction Since the limited capacity of the brain impedes us to process all sensory stimuli at once, selective attention is a crucial ability in daily life (Broadbent, 1957; Lennie, 2003). Depending on the behavioral goal in a certain situation, attentional selection in the visual domain can be endogenously deployed based on spatial locations (e.g., Posner, 1980), objects (e.g., Duncan, 1984; Scholl, 2001) and even features of objects (e.g., Driver and Baylis, 1989; Egeth and Yantis, 1997).
The One Question That Steers You to a Happier Life
[Excerpted from You, Happier: The 7 Neuroscience Secrets of Feeling Good Based on Your Brain Type by Daniel G. Amen, MD] You, Happier: The 7 Neuroscience Secrets of Feeling Good Based on Your Brain Type is written by psychiatrist, neuroscientist, and brain health expert Daniel G. Amen, MD. In this book, he reveals how to discover your brain type and tailor happiness strategies best suited to your brain type.
The Secret “Me Too” Society
With the onset of the “Me Too” movement in 2017, the extent of sexual abuse and harassment was brought onto the public stage. As notable celebrities and other high-profile people began to openly share their stories, it provided a forum for “everyday” people to also open up about their experiences of abuse.
Why are Millennials So Sick Physically and Mentally?
Most people equate chronic illnesses with the elderly, but a recent Harris Poll study reveals that 44% of millennials born between 1981-1988 have been diagnosed with at least one chronic health condition. What’s really alarming is that 4 of the top 5 chronic health conditions (and 6 of the top 10) among millennials fall into the mental or behavioral health category, according to a study from Blue Cross Blue Shield. And the rates for these conditions are rising dramatically.
Editorial: Dynamic Functioning of Resting State Networks in Physiological and Pathological Conditions
Introduction Modern neuroimaging techniques, such as Magnetic Resonance Imaging (MRI), allow for study of the brain from structural and functional perspectives. Particularly, resting state networks' (RSNs) connectivity explores the integration of activity across distant brain areas. In recent years a growing number of studies have shown that the resting state may provide a sensitive and valuable tool able to study cerebral functioning in normal and pathological conditions.
Psychedelic drugs: neurobiology and potential for treatment of psychiatric disorders
Abstract Renewed interest in the use of psychedelics in the treatment of psychiatric disorders warrants a better understanding of the neurobiological mechanisms underlying the effects of these substances.
Combination therapy with transcranial magnetic stimulation and ketamine for treatment-resistant depression: A long-term retrospective review of clinical use
Abstract Background Both transcranial magnetic stimulation (TMS) and infused ketamine are recognized treatments for patients suffering from major depressive disorder (MDD). A novel therapy named combination TMS with ketamine (CTK) is introduced. This retrospective review examined the safety and clinical benefits of CTK in patients suffering from treatment-resistant depression (TRD) during the routine practice of psychiatry in a private clinic.
Magnetic resonance imaging of mouse brain networks plasticity following motor learning
Loading metrics Open Access Peer-reviewed Research Article Alexandra Badea , Kwan L. Ng , Robert J. Anderson, Jiangyang Zhang, Michael I. Miller, Richard J. O’Brien Alexandra Badea, Kwan L. Ng, Robert J. Anderson, Jiangyang Zhang, Michael I. Miller, Richard J. O’Brien Published: May 8, 2019 https://doi.org/10.1371/journal.pone.0216596 Figures Abstract We do not have a full understanding of the mechanisms underlying plasticity in the human brain.
Predictors of Fighting Ability Inferences Based on Faces
Introduction Male intra-sexual competition is considered an important factor of selective pressure (Puts, 2010; Třebický et al., 2012; Hill et al., 2013; Sell et al., 2017), because it is associated with access to resources via rise in social hierarchy and consequently also with broader mating opportunities.
Integrated Laplacian‐based phase unwrapping and background phase removal for quantitative susceptibility mapping
Quantitative susceptibility mapping (QSM) is a recently developed MRI technique that provides a quantitative measure of tissue magnetic susceptibility. To compute tissue magnetic susceptibilities based on gradient echoes, QSM requires reliable unwrapping of the measured phase images and removal of contributions caused by background susceptibilities. Typically, the two steps are performed separately.
The Fabric of Meaning and Subjective Effects in LSD-Induced States Depend on Serotonin 2A Receptor Activation
A core aspect of the human self is the attribution of personal relevance to everyday stimuli enabling us to experience our environment as meaningful [ 1 ]. However, abnormalities in the attribution of personal relevance to sensory experiences are also critical features of many psychiatric disorders [ 2, 3 ]. Despite their clinical relevance, the neurochemical and anatomical substrates enabling meaningful experiences are largely unknown.
Temperature-activated ion channels in neural crest cells confer maternal fever-associated birth defects
Cardiac and craniofacial birth defects are common, but many cannot be attributed to specific mutations. An environmental trigger associated with these birth defects is fever during the first trimester. Using chick or zebrafish embryos, Hutson et al. found that hyperthermia activated temperature-sensitive TRPV1 and TRPV4 ion channels in neural crest cells, which give rise to the tissues affected by the birth defects.
Implementing magnetic resonance imaging into clinical routine screening in patients with psychosis?
You have accessRestricted access Implementing magnetic resonance imaging into clinical routine screening in patients with psychosis? Stefan Borgwardt, André Schmidt The British Journal of Psychiatry Oct 2017, 211 (4) 192-193; DOI: 10.1192/bjp.bp.117.199919
Women Have More Active Brains
Largest functional brain imaging study to date identifies specific brain differences between women and men, according to a new report in the Journal of Alzheimer’s Disease. In the largest functional brain imaging study to date, the Amen Clinics (Newport Beach, CA) compared 46,034 brain SPECT imaging studies provided by nine clinics, quantifying differences between the brains of men and women. The study is published in the Journal of Alzheimer’s Disease. Lead author psychiatrist Daniel G.
Brain Development Is Delayed In ADHD
By Christopher Fisher, PhD on July 30, 2012 in ADHD, Brain Imaging Is attention-deficit/hyperactivity disorder (ADHD) due to a delay in brain development or the result of complete deviation from typical development? In the current issue of Biological Psychiatry, Dr. Philip Shaw and colleagues present evidence for delay based on a study by the National Institutes of Health.
Brain Imaging Shows That Social Brain Circuits Are Disrupted In Autism
By Christopher Fisher, PhD on July 21, 2012 in Autism, Brain Imaging In a study of high-functioning adolescents with an autism spectrum disorder, scientists using functional brain imaging have found reduced connectivity selectively affecting parts of the brain that form circuits supporting social behavior.
Association Between Baseline Corticothalamic-Mediated Inhibitory Control and Smoking Relapse Vulnerability
[Skip to Content Landing] Figure 1.
Brain imaging and causal assessment of impairments reveals metamemory regions
Juntendo University researchers identify areas of the brain responsible for metacognitive memory evaluation in macaque monkeys. "We know how confidently we know," explains Yasushi Miyashita and colleagues at Juntendo University Graduate School of Medicine and the University of Tokyo School of Medicine in their recent report. The evaluation of how well we remember things requires a metacognitive self-monitoring of memory-states termed "metamemory".
Yale researchers find part of brain that determines how well you handle stress
Humans are amazingly resilient in crises, but some cope with life's stresses better than others. On any given day, people face any number of minor annoyances such as being stuck in traffic or spilling coffee on their shirts or forgetting their keys. Then there's the persistent stressors that come from work, relationships and finances. And there's the uncontrollable anxieties of global terrorism, mass shootings and Zika-carrying mosquitoes.
Show More
loading
Actions
Is this you?
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Get in touch with Brain
Contact Brain, search articles and posts on X, monitor coverage, and track replies from one place.
Learn more about Muck Rack