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Brandy Bardales

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Articles

Potential Involvement of Oxidative Stress, Apoptosis and Proinflammation in Ipconazole-Induced Cytotoxicity in Human Endothelial-like Cells

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By Karen Cordova, Iris Ruiz-Yance, Brandy Bardales, Ingrid Robles-Castañeda
| MDPI
1. Introduction Ipconazole is a broad-spectrum fungicide used as an agrochemical and pesticide to protect plants of various crops, turfs, ornamental flowers and conifers. Ipconazole is structurally similar to other triazole compounds used as pesticides (Figure 1), and its mechanism of action is to inhibit sterol synthesis in fungi, especially zygomycetes, ascomycetes, basidiomycetes and deuteromycetes, at concentrations of 20 g/ton of seed.
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