Introduction “Autistic burnout” is often used by autistic adults to describe a state of incapacitation, exhaustion, and distress in every area of life.1 Informally, autistic adults describe how burnout has cost them jobs, friends, activities, independence, mental and physical health, and pushed them to suicidal behavior.1,2 The Twitter hashtag #AutisticBurnout produces hundreds of urgent messages among autistic people trying to understand, prevent, or recover from autistic burnout.