Brendan Crowley on Muck Rack

Brendan Crowley

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Middletown
As seen in: Bristol Press, Nature, Wiley Online Library, Yahoo Canada, Chron, Yahoo Sports Canada, Popular Mechanics, Yahoo, Yahoo Movies Canada, JD Supra, NewsBreak and
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Articles

Discovery and development of a new oxazolidinone with reduced toxicity for the treatment of tuberculosis - Nature Medicine Original

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By Brendan Crowley , Helena I. Boshoff, Christopher Boyce, Sangmi Oh, Firat Kaya, Véronique Dartois, Aidan Boving, Gregory T. Roberston
| Nature
Abstract Linezolid, an oxazolidinone, is a cornerstone of treatment regimens for highly drug-resistant tuberculosis but cannot be used in drug-susceptible disease because of toxicity. This toxicity results from inhibition of mammalian mitochondrial protein synthesis. Here we show the development of a new oxazolidinone, MK-7762, with antitubercular activity that is better than linezolid and limited mitochondrial protein synthesis inhibition.
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City jury convicts man of sexual assault in Southington

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By Brendan Crowley 
| New Britain Herald
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Bristol urges park-goers to stop feeding geese

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By Brendan Crowley 
| Bristol Press
BRISTOL – Bristol officials are urging residents to stop feeding Canadian geese in city parks, saying the growing flocks of ornery birds are fouling up public spaces. A new plan aims to get them to move along without ruffling feathers. The two-phase plan aims to make the parks less desirable to geese, according to Bristol Parks, Recreation, Youth and Community Services. Step one is to stop feeding them.
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