The Health Resources and Services Administration (HRSA) recently took steps to repropose a 340B rebate model. On May 27, 2026, it sent a prerule notice regarding the model to the White House Office of Management and Budget (OMB) for review. It also recently issued an information collection request (ICR), which provides insight into how the agency intends to operationalize a rebate-based approach that could materially alter how hospitals and other covered entities access 340B savings.