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Brian Rice

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Articles

Graph augmented transformers improve chemotherapy toxicity symptom extraction from clinical notes

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By Elia Saquand, Behzad Naderalvojoud, Maximilian Schuessler, Malvika Pillai, Brian Rice, Douglas W. Blayney, Tina Hernandez-Boussard
| Nature Verified
Abstract Chemotherapy is essential for cancer treatment but may cause adverse events requiring emergency department visits and hospitalizations, placing substantial burdens on patients and healthcare systems. Existing approaches to detect these events often rely on structured electronic health records (EHR) data, which incompletely capture patients’ symptom trajectories. Clinical notes contain richer information yet remain challenging to synthesize.
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Identifying care gaps along the HIV treatment failure cascade: A multistate analysis of viral load monitoring, re-suppression, and regimen switches in Zambia

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By Kombatende Sikombe, Noelle Le Tourneau, Brian Rice, Jake M Pry
| PLOS Medicine Verified
Loading metrics Open Access Peer-reviewed Research Article ? This is an uncorrected proof. Citation: Sikombe K, Le Tourneau N, Rice B, Pry JM, Simbeza S, Beres LK, et al. (2025) Identifying care gaps along the HIV treatment failure cascade: A multistate analysis of viral load monitoring, re-suppression, and regimen switches in Zambia. PLoS Med 22(9): e1004720.
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Large-scale single-cell profiling of stem cells uncovers redundant regulators of shoot development and yield trait variation

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By Xiaosa Xu, Michael Passalacqua, Brian Rice, Edgar Demesa-Arevalo
| BioRxiv
Abstract Stem cells in plant shoots are a rare population of cells that produce leaves, fruits and seeds, vital sources for food and bioethanol. Uncovering regulators expressed in these stem cells will inform crop engineering to boost productivity. Single-cell analysis is a powerful tool for identifying regulators expressed in specific groups of cells. However, accessing plant shoot stem cells is challenging.
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