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Brice Barbat on Muck Rack

Brice Barbat

As seen in: Wiley Online Library, Science Magazine
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Articles

Insights into dynamics and gating properties of T2SS secretins

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By Nils Bochow, Karine Rizzoti, Marianne Otte, Brice Barbat
| Science Magazine Verified
Research Article MICROBIOLOGY INTRODUCTION Recent high-resolution three-dimensional (3D) structures of bacterial secretins have revealed the structural organization of this outer membrane (OM) portal of bacterial nanomachines specialized in the translocation of large structures (1–4).
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Refining the Dynamic Network of T2SS Endopilus Tip Heterocomplex Combining cw‐EPR and Nitroxide-GdIII Distance Measurements

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By Guillaume Gerbaud, Brice Barbat, Mathilde Tribout, Emilien Etienne
| Wiley Online Library Verified
Graphical Abstract We applied cw-EPR experiments and DEER measurements with orthogonally spin-labelled systems to probe dynamics processes in the assembly of the hetero-tetrameric complex located at the tip of the T2SS endopilus core. This spectroscopic approach appeared particularly appropriate to studying the structural movements and conformational changes occurring during the formation of such heteroprotein complexes.
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