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BRIDGE-Consortium Germany e.V

As seen in: Cancer Research, European Urology
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Articles

Membranous NECTIN-4 Expression Frequently Decreases during Metastatic Spread of Urothelial Carcinoma and Is Associated with Enfortumab Vedotin Resistance

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By BRIDGE-Consortium Germany e.V, Gynaecological Oncology
| Cancer Research Verified
N. Klümper reports grants from BONFOR Program of the Medical Faculty of the University of Bonn and DFG during the conduct of the study as well as personal fees from Astellas, Novartis, Ipsen, and Photocure outside the submitted work. D.J. Ralser reports personal fees from Novartis during the conduct of the study. F. Roghmann reports grants and personal fees from Janssen-Cilag and personal fees from Roche, Merck, MSD, Pfizer, AstraZeneca, QED, and Astellas outside the submitted work. J.
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Spatial Immunephenotypes of Distant Metastases but not Matched Primary Urothelial Carcinomas Predict Response to Immune Checkpoint Inhibition

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By Franziska Erlmeier, Friedrich-Alexander-Universität Erlangen-Nürnberg, Niklas Klümper, BRIDGE-Consortium Germany e.V
| European Urology Verified
5. Conclusions Although the present study is limited by its partly retrospective nature and lack of multisampling, we demonstrate that UC underlies a dynamic immunological evolution while colonizing metastatic niches.
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