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Briney Bryan

As seen in: ACS Publications
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Articles

Direct Comparison of the Hinge-Cleaving Proteases IgdE and BdpK for LC-MS-Based IgG1 Clonal Profiling

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By Albert Bondt, Rolf Lood, Naomi de Kat, Briney Bryan
| dx.doi.org
An important part of the adaptive immune system is represented by B cells. They express a unique B cell receptor (BCR) that recognizes and binds to antigens in a very specific manner. The uniqueness and specificity of these BCRs originates from the way they are formed, namely by the somatic recombination of V-, D-, J-, and C-germline segments. (1,2) This recombination of segments can, in theory, generate more than 1013 possible BCRs, with each targeting a specific antigen.
Open in Who Shared Issue with article?

Direct Comparison of the Hinge-Cleaving Proteases IgdE and BdpK for LC-MS-Based IgG1 Clonal Profiling

|
By Albert Bondt, Naomi de Kat, Rolf Lood, Briney Bryan
| ACS Publications
An important part of the adaptive immune system is represented by B cells. They express a unique B cell receptor (BCR) that recognizes and binds to antigens in a very specific manner. The uniqueness and specificity of these BCRs originates from the way they are formed, namely by the somatic recombination of V-, D-, J-, and C-germline segments. (1,2) This recombination of segments can, in theory, generate more than 1013 possible BCRs, with each targeting a specific antigen.
Open in Who Shared Issue with article?
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