Britt B. M. Suelmann on Muck Rack

Britt B. M. Suelmann

As seen in: Nature
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Ipilimumab and nivolumab followed by chemoradiotherapy as bladder-sparing treatment in muscle-invasive bladder cancer: a phase 2 trial - Nature Medicine

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By Chantal F. Stockem, Cameron Herberts, Samantha K. Cheung, Daniel J Vis, Laura Mertens, Thierry N. Boellaard, Sara Balduzzi, SHRUTI SHARMA, Joost L. Boormans, Martine Franckena, Richard P. Meijer, Eva Schaake, Jan-Jaap J. Mellema, Bas W. G. van Rhijn, Maurits L. van Montfoort, Jeantine M. de Feijter, Johannes C. K. van der Mijn, Adam C. El Naggar, Juus L. Noteboom, Debbie G. J. Robbrecht, Britt B. M. Suelmann, Michiel S. van der Heijden
| Nature
Abstract Radical cystectomy is the most commonly used definitive local treatment for muscle-invasive bladder cancer (MIBC), yet it carries substantial perioperative complication risk, alongside major changes in urinary and sexual function. Chemoradiotherapy (CRT) is used as a bladder-sparing alternative but is usually reserved for small, solitary tumors. Highly active systemic induction therapy could enable bladder preservation for patients with more advanced tumors and reduce recurrence risk.
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