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Brittany-Amber Jacobs on Muck Rack

Brittany-Amber Jacobs

As seen in: Nature
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Articles

Identifying phenotype-genotype-function coupling in 3D organoid imaging using Shape, Appearance and Motion Phenotype Observation Tool (SPOT)

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By Felix Zhou, Brittany-Amber Jacobs, Adam Norton-Steele, Xiaoyue Han, Linna Zhou, Thomas Carroll, Carlos Puig Verified, Joseph A. Chadwick, Xiao Qin, Richard Lisle, Lewis Marsh, Helen Byrne, Heather Harrington, Xin Lu
| Nature Verified
Abstract Live cells in tissue are plastic, phenotypically dynamic, and modify their function in response to genetic and environmental perturbations.
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Hookworm exposure decreases human papillomavirus uptake and cervical cancer cell migration through systemic regulation of epithelial-mesenchymal transition marker expression

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By Brittany-Amber Jacobs, Alisha Chetty, Georgia Schäfer, Sharon Prince
| Nature Verified
All methods were performed in accordance with The University of Cape Town’s guidelines and regulations. N. brasiliensis was maintained and used as described27. Briefly, N. brasiliensis L3 larvae were hatched and collected from the faecal material of Wistar rats, 5–7 days post-infection. Larvae were washed in fungizone before homogenization in Phosphate Buffered Saline (PBS) containing 1% protease inhibitor cocktail (Sigma).
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