Brunilda Balliu

Abstract Over the last ten years, there has been considerable progress in using digital behavioral phenotypes, captured passively and continuously from smartphones and wearable devices, to infer depressive mood. However, most digital phenotype studies suffer from poor replicability, often fail to detect clinically relevant events, and use measures of depression that are not validated or suitable for collecting large and longitudinal data.

Study cohorts Work in this manuscript is part of an ongoing study of BMI-discordant (ΔBMI ≥3 kg/m2) MZ twin pairs identified from the population-based Finnish twin cohorts (FTC), collected and recruited in the University of Helsinki, Helsinki, Finland. The twin study design was approved by the Ethics Committee of the Helsinki University Central Hospital, Helsinki, Finland, and all participants gave written informed consent.

1,2 na1, Brunilda Balliu3 na1, Daniel Nachun4,5, Theresia M. Schnurr6, Matthew G. Durrant4, Erik Ingelsson6, Martin Wabitsch7, Thomas Quertermous6,8, 2,4, Joshua W.