Bruno G. Galuzzi

Protein Data Set and Molecular Descriptors To train, validate, and test FeS-RedPred, we compiled a curated data set of Fe–S proteins for which both structural data and experimentally determined RP are available, all identified through a systematic literature search updated as of July 2025 ( Supporting Information File S2 ). (40−44) The data set includes small Fe–S proteins containing either binuclear [2Fe–2S] clusters or mononuclear rubredoxin-type clusters.

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Abstract To fully understand how cancer metabolism differs between primary tumors and metastases, resolving cell metabolism with spatial precision is essential. Yet, spatial fluxomics lags behind advancements in spatial transcriptomics. To address this gap, we generated high-resolution spatial transcriptomics datasets from paired primary colorectal tumors and liver metastases, designed to capture metabolic adaptations across distinct tumor sites.