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Bruno Gutiérrez Cuevas on Muck Rack

Bruno Gutiérrez Cuevas

As seen in: El País, BioRxiv, Inmodiario
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Articles

Structural evolution of nitrogenase enzymes over geologic time

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By Bruno Gutiérrez Cuevas, Franka Detemple, Kaustubh Amritkar, Amanda Garcia
| BioRxiv
Abstract Life on Earth is more than 3.5 billion years old, nearly as old as the age of the planet. Over this vast expanse of time, life and its biomolecules adapted to and triggered profound changes to the Earth s environment. Certain critical enzymes evolved early in the history of life and have persisted through planetary extremes.
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Nitrogenase structural evolution across Earth s history

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By Bruno Gutiérrez Cuevas, Franka Detemple, Kaustubh Amritkar, Amanda Garcia
| BioRxiv
Abstract Life on Earth is more than 3.5 billion years old nearly as old as the age of the planet. Over this vast expanse of time, life and its biomolecules adapted to and triggered profound changes to the Earth s environment. Certain critical enzymes evolved early in the history of life and have persisted through planetary extremes.
Open in Who Shared Issue with article?

Ancestral structure prediction reveals the conformational impact of the RuBisCO small subunit across time

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By Bruno Gutiérrez Cuevas, Betul Kacar, Kaustubh Amritkar
| BioRxiv
Abstract Ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) is an ancient protein critical for CO2-fixation and global biogeochemistry. Form-I RuBisCO complexes uniquely harbor small subunits that form a hexadecameric complex together with their large subunits. The small subunit protein is thought to have significantly contributed to RuBisCO s response to the atmospheric rise of O2 ~2.5 billion years ago, marking a pivotal point in the enzyme s evolutionary history.
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