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Articles by Bryan Le
Retrosplenial cortex maturation aligns with the transition from infant forgetting to persistent memory
Keywords infantile amnesia memory retrosplenial cortex TRAP2 neural circuits brain clearing light sheet fluorescence microscopy fear conditioning Research topic(s) CP: neuroscience Introduction Infantile amnesia describes a process by which episodic memories formed early in life are rapidly forgotten.1,2,3 In contrast, memories formed later can last for decades.
Ensurance.com Launches Modern Platform Connecting Insurance Shoppers with Agents
Ensurance.com modernizes the connection between online insurance shoppers and licensed agents for clearer, faster, and more responsive guidance.
Single-cell analysis of human fibrous dysplasia bone reveals a fibrotic transcriptome and GNAS variants in endothelial, perivascular, and stromal cells
Keywords Gs-GPCR signaling genetic mosaicism single-cell RNA sequencing single-cell genotyping bone formation fibrous dysplasia of the bone fibrous dysplasia/McCune-Albright syndrome skeletal dysplasias Introduction Somatic, genetic mosaicism is a leading cause of disease across the human lifespan1 and is a major contributor to solid and hematologic malignancies,2 developmental disorders,3 dermatologic diseases,4 X-linked syndromes,5,6,7,8 growth disorders,8,9 and skeletal dysplasias.10,11...
In Response to Utilization of Artificial Intelligence in the Creation of Patient Information on Laryngology Topics
Letter to the Editor In Response to Utilization of Artificial Intelligence in the Creation of Patient Information on Laryngology Topics Quynh-Lam Tran BS, Quynh-Lam Tran BS Department of Head and Neck Surgery, Kaiser Permanente, Oakland Medical Center, Oakland, California, USA Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA Search for more papers by this authorPauline P. Huynh MD, Pauline P.
Factors associated with grade progression in pancreatic neuroendocrine tumors
Endocrine-Related Cancer is committed to supporting researchers in demonstrating the impact of their articles published in the journal. The two types of article metrics we measure are (i) more traditional full-text views and pdf downloads, and (ii) Altmetric data, which shows the wider impact of articles in a range of non-traditional sources, such as social media. More information is on the Reasons to publish page.
Utilization of Artificial Intelligence in the Creation of Patient Information on Laryngology Topics
Objective To evaluate and compare the readability and quality of patient information generated by Chat-Generative Pre-Trained Transformer-3.5 (ChatGPT) and the American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS) using validated instruments including Flesch–Kincaid Grade Level (FKGL), Flesch Reading Ease, DISCERN, and Patient Education Materials Assessment Tool for Printable Materials (PEMAT-P).
Effects of Spermine Synthase Deficiency in Mesenchymal Stromal Cells Are Rescued by Upstream Inhibition of Ornithine Decarboxylase
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Reducing Sialylation Enhances Electrotaxis of Corneal Epithelial Cells
1. Introduction Corneal wound healing is a complex, dynamic process in which a host of different signals are integrated to efficiently heal the wound. One such signal is the endogenous wound electric field, which serves as an important cue to guide cell migration [1,2]. Notably, the rate of corneal wound healing is strongly correlated with the strength of the wound electric field [3,4].
Nonprofit Organizations Expert Witness Jess Birken
Jess Birken, MNM, Esq. Jess is the owner of Birken Law Office PLLC, a boutique law firm serving nonprofits and charitable entities with their compliance and operational issues. Jess empowers nonprofits to achieve their mission by doing things right. She connects clients with the right tools, right coaching and right contacts.
Do Republicans want to eliminate Medicare and Social Security?
English, Healthcare, Joe Biden, Misinformation (Tiếng Việt) Claim: Some Republicans want to phase out Medicare and Social Security, two popular and expensive social programs run by the federal government to aid seniors. Rating: This claim is MOSTLY TRUE. Despite claims to the contrary by many Republicans, such as Rep. Marjorie Taylor Greene famously yelling that Biden was a liar, Republicans have proposed policies that would weaken Medicare and Social Security.
Đảng Cộng hòa có muốn loại bỏ Medicare và An sinh xã hội hay không?
Skip to content Chương Trình Y Tế, Joe Biden, Tiếng Việt (English) Giả định: Một số đảng viên Cộng hòa muốn loại bỏ dần Medicare và An sinh xã hội, hai chương trình xã hội phổ biến và tốn kém do chính phủ liên bang điều hành để hỗ trợ người cao tuổi. Thẩm định: Tuyên bố này HẦU NHƯ ĐÚNG.
Có phải Tổng Thống Biden phản ứng quá chậm với khinh khí cầu Trung Quốc?
Skip to content (English) Giả định: Tổng Thống Biden đã phản ứng quá chậm với khinh khí cầu Trung Quốc, cho phép vật thể lạ hoàn thành nhiệm vụ trước khi bắn hạ Thẩm định: Giả định này là SAI. FBI muốn đảm bảo không có dân thường nào bị thương trong vụ bắn hạ khinh khí cầu cũng như mong muốn thu hồi các mảnh vỡ của khinh khí cầu để phục vụ công tác điều tra nên chỉ bắn hạ sau khi vật thể lạ đã băng qua nước Mỹ.
Was President Biden Too Slow to React to the Chinese Balloon?
(Tiếng Việt) Claim: President Biden was too slow to act in response to the Chinese balloon, allowing it to complete its mission before shooting it down. Rating: This claim is FALSE. The Biden White House was aware of the balloon as soon as it entered the U.S. but did not shoot it down over land for safety and so that the balloon could be recovered. On January 28th, a white balloon the size of three buses was spotted hovering over Montana by sharp-eyed citizens.
Hot chocolate and cold oysters: Inside the big, sexy lie of edible aphrodisiacs
Food historian Samantha Bilton tells me that chocolate was primarily consumed back then as a holistic health drink – something “very bitter, [and] almost medicinal”, she says – rather than something to get you in the mood for love. It wasn’t until the 19th century that chocolate started being produced in a solid form, with the invention of milk chocolate arriving only in 1879. “There are some studies that point to certain compounds in chocolate producing an aphrodisiac effect,” she says.
Rib Fractures in Professional Baseball Pitchers: Mechanics, Epidemiology, and Management
Abstract Pitching is a complex kinetic chain activity requiring the transfer of energy from the lower body, through the core and trunk, and finally through the arm to generate explosive acceleration of the baseball. As a result, large forces are generated in the trunk musculature and rib attachments from the late cocking phase of pitching through deceleration. The repetitive cumulative load and high pitch velocities put professional pitchers at risk of rib stress fracture.
Artificial Intelligence and Firm Performance: Does Machine Intelligence Shield Firms from Risks?
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Teens Get Hammered on Hand Sanitizer
Home News By Bryan Le 04/24/12 Underage drinkers distill their own liquor from household products, landing some in the ER. An un-sanitary habit Photo via Hand sanitizer apparently tastes like "vodka and bugspray," which hardly seems like an alluring cocktail. But it is the poison-of-choice for a growing number of teens. Most recently, six LA teens drank enough hand sanitizer to land themselves in the hospital, leaving officials worried that the drink is becoming trendy again.
Bath Salts Testers Play Cat-and-Mouse
Home News By Bryan Le 07/16/12 A drug-testing company chief tells The Fix about his battle to keep pace with the ever-changing elements of bath salts. Street chemists mix it up to keep it legal. Photo via How do you test for a drug with an ever-changing chemical composition? That's what Dr. Harry Leider, Chief Medical Officer of testing company Ameritox, is trying to figure out. His target?
New Night-Out Tactic: The "Drunk Phone"
Home News By Bryan Le 07/13/12 Young drinkers carry dedicated low-end cell phones when they go out to get smashed, to avoid risking their precious smart devices. At least the numeric keypad could stop some drunk texting. Photo via Technology is amazing. In 1969, we used a computer with a 0.043 MHz processor to put a man on the moon.
Clutterers Anonymous: Help for Hoarders
Home News By Bryan Le 05/11/12 Hoarding is a televised curiosity for many—but a very real, damaging addiction to members of Clutterers Anonymous. Clutter can rule you. Photo via You've probably seen them on Hoarders—people who clutter their home with so many things that it gets out of control. The afflicted accumulate more things than they'll ever need and have trouble letting go of the things they have. Like all addictions, the causes are complicated.
Wild Dolphins Guide Addicts Through Rehab
Home News By Bryan Le 02/29/12 One facility in Hawaii treats recovering addicts via unscripted ocean encounters with spinner dolphins. Native Hawaiian spinner dolphins help patients get squeaky clean. Photo via The Hawaii Island Recovery rehab facility has a new and unorthodox approach: wild dolphin-assisted psychotherapy.
10 Crazy Attempts to Get High
sarpa salpa.png Description: The idea that you can get high from eating the heads of sea bream might sound fishy, but it's true—just ask the two Frenchmen who tripped out after a seafood dinner in 2006. One of them, aged 90, suffered auditory hallucinations and terrifying nightmares for the next two nights, while his 40-year-old companion saw horrible sights for 36 straight hours. The pair had been hit by a grave case of icthyoallyeinotoxism—the technical term for getting high off fish.
Cops Still Bust People Using $2 Drug Test That Mistakes Bird Poop For Cocaine
By Bryan Le 10/28/19 Law enforcement still depends on a cheap, unreliable drug test to make arrests. A bunk test with junk results. Chernetskaya | Dreamstime.com Police once leveled charges on someone for cocaine that turned out just to be bird poop. Another time, for meth that was actually some flakes of donut glaze. Surprisingly, these arrests weren’t just in-the-moment visual mistakes, they’re the result of false positive drug test results.
Inside Bernie Sanders' Plan To End Federal Marijuana Prohibition
By Bryan Le 10/28/19 His ambitious plan includes billions in grants toward expunging convictions and minority-owned MJ businesses. Legalize it and free those arrested for it, says Sanders. Jhansen2 | Dreamstime.com At 4:20 on October 24, the Bernie Sanders campaign released his policy roadmap to marijuana legalization.
Video Games: A South Korean National Pastime…Or Addiction?
By Bryan Le 10/21/19 The digitized nation grapples with the good and bad of competitive computer gaming. ID 104888383 © Innovatedcaptures | Dreamstime.com South Korea’s $13 billion competitive gaming industry doesn’t like the World Health Organization’s addition of "gaming disorder" to its 2022 revision of the International Classification of Diseases. Mental health experts in the country say a nuanced examination of the hobby is long overdue.
Chocolate Chip Cookies Are Like Cocaine To Your Brain
By Bryan Le 10/21/19 The addiction response from the delicious baked treats are indistinguishable from drugs. ID 132203221 © Chernetskaya | Dreamstime.com Researchers at the University of Bordeaux say that the brain’s response to chocolate chip cookies is the same as its response to cocaine and THC. While such equivalencies are overblown, the claims are rooted in sound science—a testament to the complexity of mental health and addiction.
Shia LaBeouf Says Co-Star With Down Syndrome Saved Him From Alcohol
By Bryan Le 10/15/19 His “The Peanut Butter Falcon” co-star Zack Gottswagen made LaBeouf promise to never do “that kind of stuff again.” He needed to hear some honest words. Actor Shia LaBeouf told interviewers on the UK’s Channel 4 that he was saved by tough love doled out by his The Peanut Butter Falcon co-star Zack Gottsagen. At the time, LaBeouf was dealing with the blowback from his drunken arrest, during which he launched into a racist rant against his arresting officers.
Prince Harry, Ed Sheeran Team Up To Bring Awareness To Gingers, er, Mental Health
By Bryan Le 10/14/19 Their mental health awareness video starts with a gag—Sheeran "mistakenly" believing their team-up was to bring ginger awareness. The pair wants you to support a long-suffering people. Instagram Prince Harry and musician Ed Sheeran teamed up to bring awareness to Mental Health Day, October 10, taking a moment to run a gag about their shared hair color. On a video shared to both of their Instagram accounts, Sheeran seems to have "mistaken" the purpose of their get-together.
Aaron Carter Takes Drug Test On Instagram
By Bryan Le On 10/08/19 The stunt was a response to rumors that he was using drugs. Musician Aaron Carter posted a video on Instagram of himself taking a drug test and showing off the clean results last Thursday. In the video, he directly addresses Radar Online, which ran a story about what seemed to be a line of white powder and a credit card visible in a recent live stream by Carter. “Radar Online, I’m just letting you know, I’m taking a drug test right now.
Pennsylvania Sees Drop In Overdose Deaths For First Time In Years
By Bryan Le On 10/08/19 An analysis by the DEA found that in 2018, Pennsylvania saw an encouraging 18% drop in fatal overdoses. A new DEA report finds that the state of Pennsylvania saw an overall 18% drop in overdose deaths in 2018, the first drop after years of increasing rates. Southwestern counties in Pennsylvania saw the most improvement, seeing a 41% reduction in fatal overdoses.
Can Video Games Help Treat Depression?
By Bryan Le 07/29/19 Some believe that a mind at play experiences beneficial neurological effects. It's not just a distraction, it wakes up reward pathways and the hippocampus. Doctor_bass | Dreamstime.com Video games could be beneficial for those suffering from depression, some experts believe. It may seem counterintuitive as players seem to use video games to isolate and distract themselves from the world, but the mind at play helps people feel more confident and energetic.
Rob Lowe Reflects On 29 Years Of Sobriety
By Bryan Le 05/13/19 The actor shared a message of positivity on Instagram as he celebrated the milestone. Randy Miramontez | Dreamstime.comv Actor Rob Lowe celebrated 29 years sober from drugs and alcohol in an Instagram post. In the caption of a photo of his younger self, he left some encouraging words to anyone who finds themselves on a similar path to his. “Today I celebrate 29 years of sobriety.
There’s Nothing ‘Vanilla’ About Vanilla
According to legends of the indigenous Totonac people of Mexico, in a time before vanilla was cultivated, there once lived the beautiful princess Tzacopontziza of the Totonocopan kingdom. A young prince named Zkatan-Oxga saw her picking flowers for a temple offering one day. Overcome with passion, he whisked her away into the lush forest. But they were stopped by the temple priests and executed on the spot for their transgressions.
Jamie Lee Curtis: Sobriety Changed Everything
Now coming up on her 60th birthday, movie star Jamie Lee Curtis is focused on her legacy. “I want to die having said something,” she told USA Today. Sponsored adThis sponsor paid to have this advertisement placed in this section. Curtis stars in the newest Halloween film, re-assuming her debut role as Laurie Strode to once again face the masked murderer Michael Myers. Between that first starring role and this most recent redux, Curtis has played a wide range of characters in a variety of genres.
Cerebral Palsy Beer Raises Disability Awareness
The “beach-house-relaxed” Cliffside Malibu claims to provide an oasis for recovering addicts and alcoholics. And that’s just what you'll get—if you’ve got the cash.Alumni have high praise for this this New Jersey program which offers customized treatment plans and holistic care to its college-aged clientele.
Steven Tyler Surprises Drug Court Graduates With Commencement Speech
Graduates of the Maui Drug Court’s 62nd program got a special treat when legendary rocker Steven Tyler came to their courtroom to offer some advice from his own experiences.“My name’s Steven,” he introduced himself. “I’m an alcoholic and a recovering drug addict.” Sponsored adThis sponsor paid to have this advertisement placed in this section.
Teens Using Trendy JUUL May Be Vaping A Pack's Worth Of Nicotine A Day
Easily concealable and highly potent, JUUL has become the go-to vape product for high schoolers and young adults in the U.S. It’s popular enough to have its own verb, “JUULing.” (According to the Truth Initiative, 25% of the 15-to-24-year-old users surveyed call their habit JUULing instead of vaping.)Worryingly, it seems like many young users aren’t even sure what they’re breathing in—the Truth Initiative reveals that 37% of the same surveyed youths don’t know if they’re inhaling nicotine or...
Bill Nye The Science Guy Doesn't Get High But He Is Into Pot Legalization
Bill Nye The Science Guy Doesn't Get High But He Is Into Pot Legalization “One time in college I tried it, and I’m not good at smoking. I didn’t put in the hours to get good at smoking. But you guys� knock yourselves out.� Bill Nye, colloquially titled “The Science Guy,� said in a NowThisinterview that he welcomes the societal benefits of legalization, though he isn’t a fan of using the drug himself.
Ohio Opioid Crisis Set to Shape the 2018 Election
As the opioid crisis continues to grow in scope and affect more and more families, politicians in Ohio have taken heed and begun spinning their talking points about the issue. Addressing the crisis directly paid off for Sen. Robert Portman, who won his re-election in 2016 with 58.3% of the vote.
Today at 3 pm: Join Our Twitter Chat on Rx Drugs!
Home News By Bryan Le 05/14/13 How did America get hooked on prescription pills? And what can we do about it? Join us with our co-hosts Phoenix House on #rxchat! What to do about pill popping? Many of the most dangerous drugs of abuse aren't illegal—in your home and dealt by your doctor, prescription drugs are highly addictive and highly available. Teens looking for a quick fix will often simply pop into their parents' medicine cabinets and overdose rates are a national tragedy.
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