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Coronaviruses reprogram the tRNA epitranscriptome to favor viral protein expression

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By Correa Mendonca, Buigues Bisquert
| gla.ac.uk
Muscolino, E. et al. (2026) Coronaviruses reprogram the tRNA epitranscriptome to favor viral protein expression. Nature Communications, (doi: 10.1038/ s41467-026-69700-w) (PMID:41714626) (Early Online Publication) Text 379123.pdf - Published Version Available under License Creative Commons Attribution. 3MB Abstract Coronaviruses genomes are enriched in suboptimal A- and U-ending codons, which are typically associated with reduced translation efficiency due to limited cognate tRNA availability.
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