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Bujanda Cundin on Muck Rack

Bujanda Cundin

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Articles

A coordinated transcriptional program controls de novo Golgi biogenesis

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By Bujanda Cundin, De Cegli, Nicolina Cristina
| link.springer.com
Cells recover Golgi stacks after enzyme-mediated inactivation of preexisting organelle In our previous study, we observed that incubating HeLa cells expressing ManII-HRP with H2O2 and DAB resulted in the deposition of a DAB polymer that crosslinked the lumenal contents of Golgi cisternae, thereby fully inactivating the Golgi apparatus (Jollivet et al, 2007).
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D1 dopamine receptor antagonists as a new therapeutic strategy to treat autistic-like behaviours in lysosomal storage disorders - Molecular Psychiatry

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By de Risi, di Bruno Eugenio, De Leonibus, Bujanda Cundin
| link.springer.com
Abstract Lysosomal storage disorders characterized by defective heparan sulfate (HS) degradation, such as Mucopolysaccharidosis type IIIA-D (MPS-IIIA-D), result in neurodegeneration and dementia in children. However, dementia is preceded by severe autistic-like behaviours (ALBs), presenting as hyperactivity, stereotypies, social interaction deficits, and sleep disturbances.
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