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The impact of asymptomatic kidney stones on disease progression in autosomal dominant polycystic kidney disease - BMC Nephrology
In this study, we demonstrated that the presence of asymptomatic nephrolithiasis (N+) in patients with ADPKD is associated with a significantly greater decline in renal function, as measured by ΔeGFR, compared to nephrolithiasis-negative (N-) patients. Specifically, we found that ΔeGFR was significantly higher in the N + group (16.53 mL/min/1.73 m²) than in the N- group (12.82 mL/min/1.73 m², p = 0.008).
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