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As seen in: JAMA Oncology
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Survival and Outcomes After Noncompletion of Treatment for Anal Cancer-Reply

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By Sunil Patel, Michael Raphael, Susan B. Brogly, Byline Order
| JAMA Oncology Verified
In Reply We would like to thank Jain et al and Garfinkle et al for their thoughtful comments on our recent Original Investigation.1 Jain et al inquired about those who received higher doses of radiation (54-59 Gy). We report a protective association between higher dose of radiation and lower all-cause death (adjusted hazard ratio [aHR], 0.75; 95% CI, 0.56-1.01). Data are unavailable to explore grade 4 hematologic and nonhematologic toxic effects.
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